3-氨基-1，2，4-三唑

產品名稱（Product Name）

3-氨基-1，2，4-三唑

產品編號 （Product NO）

HZA-1101

英文名稱

3-Ami,2,4-triazole

CAS 編號 (CAS NO)

1022-79-3

密度 1.1380
熔點 149-156°C
溶解性 Soluble in water (280 g/l) at 20 °C, methanol, ethanol, chloroform, and ethyl acetate (slightly). Insoluble in ether, and acetone.
產品介紹 3-Ami,2,4-triazole is a small molecule irreversible inhibitor of catalase, an enzyme responsible for converting cellular H2O2 into H2O and O2. Impeding the natural clearance of H2O2 from the cell by catalase has proven useful in studies investigating free radical-mediated damage of cardiac tissue in ischemia. 3-Ami,2,4-triazole also shows inhibition of imidazoleglycerol-phosphate dehydratase (HIS3) activity, which interrupts the biosynthesis of histidines. When 3-Ami,2,4-triazole is diazotized, the resulting 3-Diazo-1,2,4-triazole is shown to react specifically with tryptophan at acidic pH, presenting a method for determining the tryptophan content of proteins.
別名 3-氨基-1,2,4-三氮唑;3-氨基-1,2,4-三氮雜茂;氨基三唑;殺草強;Aminotriazole;Amitrol;3-AmiH-1,2,4-triazole
應用 An irreversible catalase inhibitor

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